Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454967 | 0.86 | THRB (0.51) | THRBALDH1A1CYP3A4TSHRPRKAB2 | |
| SCHEMBL28037124 | 0.81 | TSHR (0.47) | THRBALDH1A1CYP3A4TSHRPTPN11 | |
| SCHEMBL29077536 | 0.81 | THRB (0.52) | THRBALDH1A1CYP3A4TSHRPTPN11 | |
| SCHEMBL8729334 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL8729361 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL8728023 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL8728018 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL8729288 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL8724323 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL8728206 | 0.80 | THRB (0.42) | THRBALDH1A1CYP3A4TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247377-A | PROCESS FOR PRODUCING ANISOTROPIC LIQUID CRYSTAL LAYERS ON A SUBSTRATE | ROHM GMBH CHEMISCHE FABRIK (DE) | 1993-09-21 | — | — | US | disclosed |