SCHEMBL28037124

SCHEMBL28037124

C=CC(=O)OCCCCCCCC.N#Cc1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
HPGD P15428 4/20 0.47
ALDH1A1 P00352 6/20 0.43
CYP3A4 P08684 4/20 0.43
LMNA P02545 3/20 0.42
THRB P10828 2/20 0.41
THRA P10827 1/20 0.41
PTPN11 Q06124 1/20 0.41
CNR2 P34972 1/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA4 P48058 1/20 0.40
SOAT1 P35610 2/20 0.39
KDM4E B2RXH2 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31454967 0.85 THRB (0.51) TSHRHPGDALDH1A1CYP3A4THRB
Acrylic Acid Ethyl Ester SCHEMBL28318010 0.84 ALDH1A1 (0.44) HPGDALDH1A1LMNATHRBGRIA2
Benzonitrile SCHEMBL27594826 0.84 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4LMNA
SCHEMBL2692271 0.82 APP (0.54) HCAR2AKR1B1MEN1KMT2A
SCHEMBL28084501 0.82 TSHR (0.59) TSHRALDH1A1CYP3A4LMNAMAPK1
SCHEMBL9450852 0.81 THRB (0.49) TSHRALDH1A1CYP3A4THRBPTPN11
Benzoic Acid SCHEMBL2897121 0.81 GRIA2 (0.43) HPGDALDH1A1LMNAGRIA2GRIA4
Decane SCHEMBL9620442 0.80 ESR2 (0.53) TSHRHPGDALDH1A1GRIA2GRIA4
Octane SCHEMBL9620215 0.80 ESR2 (0.53) TSHRHPGDALDH1A1GRIA2GRIA4
Benzene SCHEMBL342570 0.78 TSHR (0.75) TSHRHPGDALDH1A1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104994837-A Cosmetic compositions comprising wax dispersions OREAL 2015-10-21 CN disclosed