Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9234843 | 1.00 | THRB (0.55) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Phosphoric Acid SCHEMBL1100985 | 1.00 | THRB (0.55) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Phosphoric Acid SCHEMBL9234978 | 1.00 | THRB (0.55) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Methacrylic Acid SCHEMBL27731191 | 0.94 | THRB (0.50) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Benzene SCHEMBL95868 | 0.94 | THRB (0.50) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Phosphoric Acid SCHEMBL16950259 | 0.94 | THRB (0.50) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL11233731 | 0.91 | THRB (0.52) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL19409375 | 0.91 | THRB (0.64) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL15030 | 0.91 | — | — | |
| Phosphoric Acid SCHEMBL28996617 | 0.90 | THRB (0.47) | THRBTSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026650-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | DENTSPLY SIRONA INC. (US) | 2023-01-26 | — | — | US | claimed |
| EP-4072503-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | Dentsply Sirona Inc. (US) | 2022-10-19 | — | — | EP | claimed |
| WO-2021116275-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | DENTSPLY SIRONA INC. (US) | 2021-06-17 | — | — | WO | claimed |
| EP-3834805-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | DENTSPLY SIRONA Inc. (US) | 2021-06-16 | — | — | EP | claimed |
| US-9333148-B2 | Polymerizable composition and dental material | KURARAY NORITAKE DENTAL INC. (JP) | 2016-05-10 | — | — | US | claimed |
| US-9326917-B2 | Dental masking compound | VOCO GMBH (DE) | 2016-05-03 | — | — | US | claimed |
| US-20140138864-A1 | KIT AND METHOD FOR INDIRECT CHAIRSIDE PRODUCTION OF COMPOSITE INLAYS | VOCO GMBH (DE) | 2014-05-22 | — | — | US | claimed |
| US-8329845-B2 | Divided redox-curing type composition | KURARAY NORITAKE DENTAL INC. (JP) | 2012-12-11 | — | — | US | claimed |
| US-8247471-B2 | Polymerizable composition | GC CORPORATION (JP) | 2012-08-21 | — | — | US | claimed |
| US-20120093741-A1 | DENTAL MASKING COMPOUND | VOCO GMBH (DE) | 2012-04-19 | — | — | US | claimed |
| US-5866631-A | POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. | TOKUYAMA CORPORATION (JP) | 1999-02-02 | — | — | US | claimed |
| US-12324717-B2 | Dental restorative set and method of restoring tooth | GC CORPORATION (JP) | 2025-06-10 | — | — | US | disclosed |
| WO-2024150826-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2024-07-18 | — | — | WO | disclosed |
| US-20240199494-A1 | ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF | Kuraray Noritake Dental lnc. (JP) | 2024-06-20 | — | — | US | disclosed |
| EP-4378967-A1 | (METH)ACRYLAMIDE COMPOUND, MONOMER COMPOSITION, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL | Mitsui Chemicals, Inc. (JP) | 2024-06-05 | — | — | EP | disclosed |
| US-5776655-A | CONTAINING PHOTOPOLYMER | EASTMAN KODAK COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0811368-A1 | DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST | TOKUYAMA CORPORATION (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0795790-A2 | Peel-developable lithographic printing plate | EASTMAN KODAK COMPANY (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0712622-A1 | Dental composition and kit | TOKUYAMA CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0705590-A1 | Antimicrobial adhesive composition for dental use | KURARAY CO., LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026650-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | KIT, PIP5K1C, GRIK1 | THRB 3051/4885TSHR 4603/4885ALDH1A1 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.