Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.73 |
| ▸ | CA9 | Q16790 | 8/20 | 0.73 |
| ▸ | CA1 | P00915 | 7/20 | 0.73 |
| ▸ | STS | P08842 | 7/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872943 | 0.98 | CA2 (0.70) | CA2CA9CA1STSCA12 | |
| SCHEMBL27182665 | 0.98 | CA2 (0.70) | CA2CA9CA1STSCA12 | |
| SCHEMBL9451263 | 0.85 | CA2 (1.00) | CA2CA9CA1STS | |
| Hydrazine SCHEMBL28045004 | 0.82 | CA1 (0.48) | CA2CA9CA1STSCA12 | |
| SCHEMBL10558186 | 0.82 | CA1 (0.47) | CA2CA9CA1CA12 | |
| SCHEMBL17681373 | 0.80 | CA1 (0.45) | CA2CA9CA1 | |
| SCHEMBL4431267 | 0.80 | CA1 (0.45) | CA2CA9CA1STSCA12 | |
| SCHEMBL17688536 | 0.80 | NFE2L2 (0.51) | CA2CA9CA1 | |
| SCHEMBL29508627 | 0.80 | NFE2L2 (0.51) | CA2CA9CA1 | |
| SCHEMBL9451543 | 0.79 | CA2 (0.61) | CA2CA9CA1STSCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| US-5192785-A | Sulfamates as antiglaucoma agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-09 | — | — | US | disclosed |
| US-5025031-A | Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants | A. H. ROBINS CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |