Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451311 | 0.89 | CA1 (0.64) | CA1CA2CA9MAOBCA12 | |
| SCHEMBL9451244 | 0.87 | CA1 (0.53) | CA1CA2CA9 | |
| SCHEMBL9451235 | 0.82 | CA1 (0.58) | CA1CA2CA9 | |
| SCHEMBL9451351 | 0.81 | CA2 (0.67) | CA1CA2CA9 | |
| SCHEMBL9451242 | 0.80 | CHRNB2 (0.55) | CA1CA2CA9 | |
| SCHEMBL9451313 | 0.80 | MAPK1 (0.55) | CA1CA2CA9MAOB | |
| SCHEMBL1268719 | 0.79 | MAOB (0.81) | MAOBMAOANR4A2 | |
| SCHEMBL2204910 | 0.78 | MAOB (0.64) | MAOBMAOANR4A2 | |
| SCHEMBL9451415 | 0.77 | KDM4E (0.51) | — | |
| SCHEMBL1013923 | 0.77 | CA12 (0.69) | CA1CA2CA9MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| US-5025031-A | Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants | A. H. ROBINS CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |