Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451622 | 0.80 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9451680 | 0.73 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9451594 | 0.72 | BTK (0.40) | BTK | |
| SCHEMBL4137619 | 0.62 | HIPK2 (0.45) | — | |
| SCHEMBL4651345 | 0.62 | EGLN1 (0.60) | — | |
| SCHEMBL4697109 | 0.62 | ALDH1A1 (0.47) | — | |
| SCHEMBL4145126 | 0.62 | ACACB (0.43) | — | |
| SCHEMBL8242559 | 0.62 | TDP1 (0.45) | — | |
| SCHEMBL7878824 | 0.61 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL1335315 | 0.61 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567223-A1 | Glutamic acid derivatives as antineoplastic agents | ELI LILLY AND COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5196424-A | Antitumor | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |