Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451919 | 0.81 | MAPT (0.54) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11562866 | 0.76 | MAPT (0.54) | MAPTALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL9451900 | 0.76 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11561735 | 0.75 | MAPT (0.56) | MAPTALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL9451995 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ELMNAGAA | |
| Itazigrel SCHEMBL564056 | 0.74 | PTGS2 (0.57) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9451956 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9547971 | 0.72 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9451895 | 0.71 | KDM4E (0.49) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9451977 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229386-A | Anticoagulants, hypotensive agents, antiallergens, antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5145860-A | Anticoagulants, vasodilators, antiinflammatory, antiallergens, enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |