Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 16/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451999 | 1.00 | CYP3A4 (0.49) | CYP3A4ALOX15ABCB1ABCC9CTSL | |
| SCHEMBL10512956 | 0.87 | CYP1A2 (0.44) | CYP3A4CTSLCTSBCTSSCTSK | |
| SCHEMBL10515016 | 0.81 | CYP3A4 (0.50) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL10515010 | 0.78 | CYP3A4 (0.49) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9742060 | 0.77 | ABCC9 (0.51) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9216552 | 0.77 | CYP3A4 (0.58) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9216538 | 0.77 | CYP3A4 (0.58) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9216547 | 0.77 | CYP3A4 (0.58) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9744107 | 0.76 | ABCC9 (0.49) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL10435142 | 0.76 | ABCC9 (0.49) | CYP3A4ALOX15ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273998-A | Process for making an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5177216-A | DIASTEREOMERIC ESTER COMPOUND USEFUL AS AN INTERMEDIATE IN THE MAKING OF AN OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0456266-A1 | Method for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds, intermediates therefor and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-11-13 | — | — | EP | disclosed |
| US-4988723-A | Hypotensive agents, vasodilation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |