Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.69 |
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453088 | 0.95 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4310750 | 0.86 | HDAC3 (0.65) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9487294 | 0.85 | HDAC1 (0.63) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7515225 | 0.85 | HDAC3 (0.77) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3381443 | 0.85 | HDAC3 (0.77) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1007408 | 0.85 | HDAC3 (0.77) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL17586111 | 0.84 | HDAC1 (0.61) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL14539300 | 0.83 | HDAC1 (0.74) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7048969 | 0.83 | FAAH (0.63) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7394977 | 0.82 | HDAC1 (1.00) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939173-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-03 | — | — | US | claimed |
| EP-0373587-A2 | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | claimed |
| US-5177108-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-4939173-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0373587-A2 | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | disclosed |