Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.50 |
| ▸ | RARG | P13631 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MDH1 | P40925 | 1/20 | 0.48 |
| ▸ | MDH2 | P40926 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888301 | 0.89 | RARB (0.57) | EPHX2HIF1ARARBSMN1; SMN2RARA | |
| SCHEMBL8696978 | 0.88 | NPC1 (0.56) | EPHX2HIF1ARARBNPC1RAB9A | |
| SCHEMBL8460298 | 0.86 | RARA (0.64) | EPHX2HIF1ARARBSMN1; SMN2RARA | |
| SCHEMBL9622187 | 0.86 | RARA (0.53) | EPHX2HIF1ARARBSMN1; SMN2RARA | |
| SCHEMBL6571384 | 0.83 | RARA (0.51) | EPHX2HIF1ARARBRARARARG | |
| SCHEMBL14425206 | 0.82 | RARA (0.50) | RARBNPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL8572597 | 0.81 | HIF1A (0.48) | EPHX2HIF1ARARBSMN1; SMN2RARA | |
| SCHEMBL9485994 | 0.81 | EPHX2 (0.57) | EPHX2RARBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9453266 | 0.81 | PPARG (0.47) | EPHX2HIF1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9453300 | 0.81 | PPARG (0.47) | EPHX2HIF1ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212203-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOGOLOGIQUES (C.I.R.D.) (FR) | 1993-05-18 | — | — | US | claimed |
| EP-0232199-B1 | AROMATIC BENZAMIDO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AS WELL AS IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-02-03 | — | — | EP | claimed |
| US-5212203-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOGOLOGIQUES (C.I.R.D.) (FR) | 1993-05-18 | — | — | US | disclosed |