Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | RARA | P10276 | 3/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | RARG | P13631 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | GOT1 | P17174 | 1/20 | 0.48 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462108 | 0.92 | RARA (0.53) | EPHX2RARARARBRARGKMT2A | |
| SCHEMBL9453263 | 0.92 | EPHX2 (0.48) | EPHX2RARARARBRARGKMT2A | |
| SCHEMBL8696978 | 0.87 | NPC1 (0.56) | EPHX2RARARARBRARGKMT2A | |
| SCHEMBL6536442 | 0.86 | RARA (0.55) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL14425206 | 0.84 | RARA (0.50) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9453208 | 0.83 | RARA (0.56) | EPHX2RARARARBRARGKMT2A | |
| SCHEMBL4936267 | 0.83 | RARA (0.65) | EPHX2RARARARBRARGKMT2A | |
| SCHEMBL9453322 | 0.83 | RARA (0.53) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9126792 | 0.83 | KMT2A (0.51) | EPHX2RARARARBRARGKMT2A | |
| SCHEMBL9486117 | 0.82 | PKM (0.53) | RARARARBRARGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232199-B1 | AROMATIC BENZAMIDO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AS WELL AS IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-02-03 | — | — | EP | claimed |