Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485994 | 0.92 | EPHX2 (0.57) | EPHX2MAPTMAPK1RARARARB | |
| SCHEMBL8462108 | 0.88 | RARA (0.53) | EPHX2RARARARBRARGMEN1 | |
| SCHEMBL6536442 | 0.82 | RARA (0.55) | ALDH1A1RARARARBRARGMEN1 | |
| SCHEMBL8696978 | 0.81 | NPC1 (0.56) | EPHX2MAPTMAPK1ALDH1A1RARA | |
| SCHEMBL14425206 | 0.80 | RARA (0.50) | ALDH1A1RARARARBRARGMEN1 | |
| SCHEMBL9453200 | 0.80 | RARA (0.50) | EPHX2MAPTRARARARBRARG | |
| SCHEMBL9453260 | 0.79 | RARA (0.48) | EPHX2MAPTMAPK1ALDH1A1RARA | |
| SCHEMBL4936267 | 0.79 | RARA (0.65) | EPHX2MAPK1ALDH1A1RARARARB | |
| SCHEMBL9453208 | 0.79 | RARA (0.56) | EPHX2MAPTALDH1A1RARARARB | |
| SCHEMBL9453322 | 0.79 | RARA (0.53) | MAPTALDH1A1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212203-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOGOLOGIQUES (C.I.R.D.) (FR) | 1993-05-18 | — | — | US | disclosed |