Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28048607 | 0.98 | ALDH1A1 (0.64) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL28329914 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL24589922 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL3424160 | 0.79 | IDO1 (0.55) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL3076524 | 0.79 | NPC1 (0.63) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL29614829 | 0.79 | NPC1 (0.63) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL29942654 | 0.79 | NPC1 (0.63) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL29966674 | 0.79 | NPC1 (0.63) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL20032701 | 0.78 | MEN1 (0.48) | ALDH1A1MAPTMAPK10MEN1ALOX12 | |
| SCHEMBL20032698 | 0.78 | MEN1 (0.48) | ALDH1A1MAPTMAPK10MEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221404-B | Can be used as the unsaturated nitrogen heterogeneous ring compound of PDE10 inhibitor | AMGEN INC. (US) | 2015-12-16 | — | — | CN | claimed |
| CN-103221404-A | Nitrogen heterocyclic compounds useful as PDE10 inhibitors | AMGEN INC | 2013-07-24 | — | — | CN | claimed |
| US-5271870-A | Process for introducing electrical conductivity into high-temperature polymeric materials | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY (US) | 1993-12-21 | — | — | US | claimed |
| US-4876032-A | ADDING SILVER NITRATE AND ALDEHYDE SOLUTIONS AND DRYING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1989-10-24 | — | — | US | claimed |
| US-4228151-A | QUINOXALINE DIOXIDE | L'OREAL (FR) | 1980-10-14 | — | — | US | claimed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-112266364-B | Preparation method of tetrahydroquinoxaline compound | 云南民族大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114524773-A | Method for synthesizing aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-111116496-B | Synthetic method of quinoxaline heterocyclic derivative | 扬州大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-112266364-A | Preparation method of tetrahydroquinoxaline compound | 云南民族大学 | 2021-01-26 | — | — | CN | disclosed |
| CN-111116496-A | Synthetic method of quinoxaline heterocyclic derivative | 扬州大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-105801630-A | Organometallic complex, and light-emitting element and light-emitting device using the organometallic complex | 株式会社半导体能源研究所 | 2016-07-27 | — | — | CN | disclosed |
| CN-103221404-A | Nitrogen heterocyclic compounds useful as PDE10 inhibitors | AMGEN INC | 2013-07-24 | — | — | CN | disclosed |
| CN-102010376-B | Synthesis of ionic liquid aqueous phase catalysis quinoxaline compound | UNIV YANCHENG TEACHERS | 2013-06-12 | — | — | CN | disclosed |
| CN-102924526-A | Organometallic complex, and light-emitting element and light-emitting device using the organometallic complex | SEMICONDUCTOR ENERGY LAB | 2013-02-13 | — | — | CN | disclosed |
| CN-102010376-A | Synthesis of ionic liquid aqueous phase catalysis quinoxaline compound | UNIV YANCHENG TEACHERS | 2011-04-13 | — | — | CN | disclosed |
| CN-101111506-A | Organometallic complex, and light-emitting element and light-emitting device using the organometallic complex | SEMICONDUCTOR ENERGY LAB (JP) | 2008-01-23 | — | — | CN | disclosed |
| US-5271870-A | Process for introducing electrical conductivity into high-temperature polymeric materials | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY (US) | 1993-12-21 | — | — | US | disclosed |
| US-4876032-A | ADDING SILVER NITRATE AND ALDEHYDE SOLUTIONS AND DRYING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1989-10-24 | — | — | US | disclosed |
| US-4228151-A | QUINOXALINE DIOXIDE | L'OREAL (FR) | 1980-10-14 | — | — | US | disclosed |