Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506134 | 0.84 | ALDH1A1 (0.68) | ATMSMN1; SMN2ALOX5HPGDLMNA | |
| SCHEMBL14881542 | 0.79 | ALOX5 (0.56) | ATMKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL10082605 | 0.79 | ALDH1A1 (0.60) | MAPK1KMT2AMEN1POLBALOX5 | |
| SCHEMBL14881406 | 0.78 | ALOX5 (0.55) | ATMKMT2AKDM4EMEN1POLB | |
| SCHEMBL7830321 | 0.78 | SMN1; SMN2 (0.56) | ATMSMN1; SMN2ALOX5LMNAALDH1A1 | |
| SCHEMBL7823334 | 0.78 | ALDH1A1 (0.67) | ATMKMT2AKDM4EMEN1POLB | |
| SCHEMBL110276 | 0.78 | CYP4F2 (0.65) | KMT2AKDM4ESMN1; SMN2LMNACYP1A2 | |
| SCHEMBL19644103 | 0.78 | GAA (0.58) | ATMKMT2AKDM4EMEN1POLB | |
| SCHEMBL29389131 | 0.78 | GAA (0.58) | ATMKMT2AKDM4EMEN1POLB | |
| SCHEMBL10144997 | 0.77 | ALOX5 (0.60) | ATMMAPK1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0395768-A1 | SUBSTITUTED ALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |
| CN-1042910-A | The allylamine derivatives that replaces, their production method and application thereof | BANYU PHARMA CO LTD (JP) | 1990-06-13 | — | — | CN | disclosed |