⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351710 | 0.79 | ALOX15 (0.43) | — | |
| SCHEMBL132297 | 0.78 | HSPA5 (0.38) | — | |
| SCHEMBL3982856 | 0.78 | — | — | |
| SCHEMBL11152568 | 0.78 | — | — | |
| SCHEMBL36019 | 0.77 | CYP3A4 (0.53) | — | |
| SCHEMBL234864 | 0.77 | CYP3A4 (0.53) | — | |
| SCHEMBL29373097 | 0.77 | CYP3A4 (0.53) | — | |
| Ethylene SCHEMBL28302708 | 0.76 | CYP3A4 (0.45) | — | |
| Formaldehyde SCHEMBL17416875 | 0.76 | CYP3A4 (0.45) | — | |
| SCHEMBL2049062 | 0.75 | SIGMAR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648358-A | Composition and method for producing the same | 德塔莱斯有限公司 | 2023-08-25 | — | — | CN | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| WO-2015103137-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | WO | claimed |
| EP-1687297-B1 | TRIAZINE DIMERS FOR THE TREATMENT OF AUTOIMMUNE DISEASES | PROMETIC BIOSCIENCES INC (CA) | 2014-06-18 | — | — | EP | claimed |
| US-7683061-B2 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC BIOSCIENCES INC. (CA) | 2010-03-23 | — | — | US | claimed |
| EP-1687297-A4 | TRIAZINE DIMERS FOR THE TREATMENT OF AUTOIMMUNE DISEASES | PROMETIC BIOSCIENCES INC (CA) | 2009-04-22 | — | — | EP | claimed |
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC PHARMA SMT LIMITED (GB) | 2007-06-28 | — | — | US | claimed |
| JP-2007512259-A | — | — | 2007-05-17 | — | — | JP | claimed |
| EP-1687297-A1 | TRIAZINE DIMERS FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Prometic Biosciences Inc. (CA) | 2006-08-09 | — | — | EP | claimed |
| WO-2005049607-A1 | TRIAZINE DIMERS FOR THE TREATMENT OF AUTOIMMUNE DISEASES | PROMETIC BIOSCIENCES INC. (CA) | 2005-06-02 | — | — | WO | claimed |
| WO-2004022542-A2 | SUBSTITUTED 1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | Grünenthal GmbH (DE) | 2004-03-18 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| US-4801721-A | Stereospecific synthesis of carboxyalkyl peptides | RYAN JAMES W (US) | 1989-01-31 | — | — | US | claimed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | claimed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | claimed |
| EP-0051190-A2 | N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation | PENNWALT CORPORATION (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | claimed |
| CN-117534595-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |
| US-3943153-A | BACTERICIDES | MERCK & CO., INC. (US) | 1976-03-09 | — | — | US | disclosed |