⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664855 | 0.92 | — | — | |
| SCHEMBL666880 | 0.92 | — | — | |
| SCHEMBL665954 | 0.92 | — | — | |
| SCHEMBL947673 | 0.80 | — | — | |
| SCHEMBL3428774 | 0.77 | — | — | |
| SCHEMBL946347 | 0.77 | SIGMAR1 (0.39) | — | |
| SCHEMBL946976 | 0.75 | SIGMAR1 (0.47) | — | |
| SCHEMBL693202 | 0.74 | — | — | |
| SCHEMBL4932949 | 0.74 | — | — | |
| SCHEMBL323151 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547288-A | Methods and compounds for treating and/or preventing netois | 朱比兰特埃皮帕德有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-111108105-B | Heterocyclic compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2023-03-31 | — | — | CN | claimed |
| EP-3887370-B1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | claimed |
| US-20210309657-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2021-10-07 | — | — | US | claimed |
| EP-3887370-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2021-10-06 | — | — | EP | claimed |
| WO-2020109190-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-04 | — | — | WO | claimed |
| CN-111108105-A | Heterocyclic compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2020-05-05 | — | — | CN | claimed |
| WO-2005075477-A1 | ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2005-08-18 | — | — | WO | claimed |
| US-6768024-B1 | CONTROLLING OBESITY, SEXUAL DYSFUNCTION OR INFLAMMATION | LION BIOSCIENCE AG (DE) | 2004-07-27 | — | — | US | claimed |
| WO-2002012166-A2 | TRIAMINE DERIVATIVE MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | LION BIOSCIENCE AG (DE) | 2002-02-14 | — | — | WO | claimed |
| EP-0028940-B1 | ANTIARRHYTHMIC TETRAHYDRONAPHTHALENE DERIVATIVES | E.R. Squibb & Sons, Inc. (US) | 1983-09-07 | — | — | EP | claimed |
| US-4302453-A | Antiarrhythmic tetrahydronaphthalene derivatives | E. R. SQUIBB & SONS, INC. (US) | 1981-11-24 | — | — | US | claimed |
| EP-0028940-A1 | Antiarrhythmic tetrahydronaphthalene derivatives | E.R. Squibb & Sons, Inc. (US) | 1981-05-20 | — | — | EP | claimed |
| US-4127578-A | Diene intermediates for indantetrols | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | claimed |
| US-4092318-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-05-30 | — | — | US | claimed |
| CN-116547288-A | Methods and compounds for treating and/or preventing netois | 朱比兰特埃皮帕德有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-111108105-B | Heterocyclic compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2023-03-31 | — | — | CN | disclosed |
| US-3982021-A | Compositions for the treatment of coronary diseases containing tetrahydronaphthyloxy-aminopropanols | E. R. SQUIBB & SONS, INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3943149-A | HYPOCHOLESTEREMIC, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-03-09 | — | — | US | disclosed |
| US-3935267-A | CARDIOVASCULAR DISORDERS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |