Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455310 | 0.94 | SIGMAR1 (0.57) | SIGMAR1LMNADRD2 | |
| SCHEMBL9455252 | 0.90 | SIGMAR1 (0.58) | SIGMAR1LMNADRD2 | |
| SCHEMBL9455290 | 0.90 | SIGMAR1 (0.62) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9455133 | 0.89 | SIGMAR1 (0.58) | SIGMAR1CCR3OPRM1OPRL1DRD4 | |
| SCHEMBL9455294 | 0.88 | SIGMAR1 (0.59) | SIGMAR1DRD2 | |
| SCHEMBL9455321 | 0.85 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL9455224 | 0.84 | OPRL1 (0.52) | SIGMAR1OPRM1OPRL1DRD4DRD2 | |
| SCHEMBL9676151 | 0.81 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL9455306 | 0.80 | OPRL1 (0.55) | SIGMAR1OPRM1OPRL1DRD4 | |
| SCHEMBL9677462 | 0.79 | SIGMAR1 (0.77) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229383-A | Treating psychotic disorders | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-07-20 | — | — | US | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |
| EP-0359790-A1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1990-03-28 | — | — | EP | disclosed |
| WO-1989007596-A1 | NEW 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-08-24 | — | — | WO | disclosed |