Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455321 | 0.97 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL9455252 | 0.92 | SIGMAR1 (0.58) | SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL9455133 | 0.89 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL9455013 | 0.88 | SIGMAR1 (0.54) | SIGMAR1DRD2 | |
| SCHEMBL9455290 | 0.88 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL9677788 | 0.86 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL9455030 | 0.84 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL9455310 | 0.83 | SIGMAR1 (0.57) | SIGMAR1DRD2 | |
| SCHEMBL9455193 | 0.82 | SIGMAR1 (0.56) | SIGMAR1DRD2 | |
| SCHEMBL9678898 | 0.82 | SIGMAR1 (0.77) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | claimed |
| EP-0359790-A1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1990-03-28 | — | — | EP | claimed |
| WO-1989007596-A1 | NEW 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-08-24 | — | — | WO | claimed |
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5229383-A | Treating psychotic disorders | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-07-20 | — | — | US | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |
| EP-0359790-A1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1990-03-28 | — | — | EP | disclosed |
| WO-1989007596-A1 | NEW 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-08-24 | — | — | WO | disclosed |