Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455447 | 0.75 | CYP19A1 (0.40) | ALDH1A1CYP3A4 | |
| SCHEMBL9787304 | 0.73 | CYP3A4 (0.38) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL9455570 | 0.71 | CASR (0.48) | SMN1; SMN2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL9787321 | 0.70 | CYP3A4 (0.43) | SMN1; SMN2ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL2819804 | 0.66 | CYP3A4 (0.44) | SMN1; SMN2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL9455534 | 0.66 | KDM4E (0.45) | ALDH1A1KDM4EMAPTCYP3A4CYP2C19 | |
| SCHEMBL4479735 | 0.66 | SYK (0.44) | SYKSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL9455538 | 0.65 | KIF11 (0.31) | SMN1; SMN2ALDH1A1GAAMAPTCYP3A4 | |
| SCHEMBL13342069 | 0.65 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10421682 | 0.63 | CYP3A4 (0.39) | ALDH1A1GAAKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196562-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-4933341-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0364765-A2 | Substituted 1,3,5-triazinetriones, process for their preparation, and their use against parasitical protozoa | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |