Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787304 | 0.77 | CYP3A4 (0.38) | CYP3A4MEN1ALDH1A1 | |
| SCHEMBL9787321 | 0.75 | CYP3A4 (0.43) | CYP3A4POLBALDH1A1 | |
| SCHEMBL9455376 | 0.75 | SYK (0.37) | CYP3A4ALDH1A1 | |
| SCHEMBL5566635 | 0.73 | CYP3A4 (0.70) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL9455534 | 0.70 | KDM4E (0.45) | CYP3A4MEN1ALDH1A1 | |
| SCHEMBL9455570 | 0.68 | CASR (0.48) | POLBMEN1ALDH1A1 | |
| SCHEMBL9455538 | 0.67 | KIF11 (0.31) | CYP3A4POLBMEN1ALDH1A1 | |
| SCHEMBL2819804 | 0.66 | CYP3A4 (0.44) | CYP3A4POLBMEN1ALDH1A1 | |
| SCHEMBL10421682 | 0.65 | CYP3A4 (0.39) | CYP3A4POLBMEN1ALDH1A1 | |
| SCHEMBL9770755 | 0.65 | CYP3A4 (0.43) | CYP19A1CYP3A4CYP3A5POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196562-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-4933341-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0364765-A2 | Substituted 1,3,5-triazinetriones, process for their preparation, and their use against parasitical protozoa | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |