⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607820 | 0.88 | CA1 (0.42) | — | |
| SCHEMBL63095 | 0.79 | — | — | |
| SCHEMBL28224141 | 0.78 | — | — | |
| SCHEMBL7920518 | 0.76 | CA1 (0.40) | — | |
| SCHEMBL31229762 | 0.76 | CA1 (0.48) | — | |
| SCHEMBL701818 | 0.74 | CA1 (0.33) | — | |
| SCHEMBL7575729 | 0.73 | — | — | |
| SCHEMBL28155658 | 0.72 | CA1 (0.56) | — | |
| SCHEMBL5265843 | 0.71 | CA1 (0.57) | — | |
| SCHEMBL3877626 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094333-A1 | NO-RELEASING NITROOXY-CHROMENE CONJUGATES | Euclises Pharmaceuticals, Inc. (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015109011-A1 | NO-RELEASING NITROOXY-CHROMENE CONJUGATES | Euclises Pharmaceuticals, Inc. (US) | 2015-07-23 | — | — | WO | disclosed |
| EP-0334853-B1 | SOFT STEROIDS HAVING ANTI-INFLAMMATORY ACTIVITY | BODOR, Nicholas S. (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0334853-A4 | SOFT STEROIDS HAVING ANTI-INFLAMMATORY ACTIVITY. | BODOR NICHOLAS S | 1990-02-26 | — | — | EP | disclosed |
| EP-0334853-A1 | SOFT STEROIDS HAVING ANTI-INFLAMMATORY ACTIVITY | BODOR, Nicholas S. (US) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989003390-A1 | SOFT STEROIDS HAVING ANTI-INFLAMMATORY ACTIVITY | BODOR NICHOLAS S (US) | 1989-04-20 | — | — | WO | disclosed |
| US-4710495-A | Soft steroids having anti-inflammatory activity | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-01 | — | — | US | disclosed |