Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057016 | 0.86 | POLB (0.38) | ALDH1A1CYP2D6CYP2C19HSD17B10CYP3A4 | |
| Hydrogen Peroxide SCHEMBL9456660 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL7616178 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8064735 | 0.82 | ESR1 (0.47) | ALDH1A1HSD17B10CYP3A4ESR1ESR2 | |
| SCHEMBL6682969 | 0.81 | KIF11 (0.42) | ALDH1A1CYP2D6CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL14402557 | 0.80 | AOC3 (0.41) | ALDH1A1CYP2C19CYP3A4HIF1AKIF11 | |
| SCHEMBL21409667 | 0.80 | CYP2D6 (0.38) | ALDH1A1CYP2D6CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL13849904 | 0.80 | AOC3 (0.41) | ALDH1A1CYP2C19CYP3A4HIF1AKIF11 | |
| SCHEMBL28312162 | 0.79 | CYP2D6 (0.44) | ALDH1A1CYP2D6CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL20986026 | 0.78 | CYP2D6 (0.43) | ALDH1A1CYP2D6CYP2C19HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617359-A | High molecular weight polyacrylamide synthesis | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-10-14 | — | — | US | claimed |
| EP-0194222-B1 | PREPARATION OF POLYMERS CONTAINING PENDANT ISOCYANATE GROUPS AND DERIVATIVES THEREOF BY EMULSION COPOLYMERIZATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5191083-A | Unsaturated monomers with pendant carbamate groups, stabilization of synthetic rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0203879-B1 | FUNCTIONALIZED MONOMERS FROM 1-(1-ISOCYANATO-1-METHYLETHYL)-3 OR 4-(1-METHYLETHENYL) BENZENE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |
| US-4853478-A | ANTIDEGRADATION MONOMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| US-4714772-A | POLYMERIZABLE ANTIDEGRADANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
| US-4694057-A | Preparation of polymers containing pendant isocyanate groups and derivatives thereof by emulsion copolymerization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0203879-A2 | Functionalized monomers from 1-(1-isocyanato-1-methylethyl)-3 or 4-(1-methylethenyl) benzene | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4617359-A | High molecular weight polyacrylamide synthesis | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0194222-A2 | Preparation of polymers containing pendant isocyanate groups and derivatives thereof by emulsion copolymerization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4604439-A | STABILIZERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-08-05 | — | — | US | disclosed |