Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.77 |
| ▸ | PTGFR | P43088 | 8/20 | 0.66 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964800 | 1.00 | ABCB11 (0.77) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL4875027 | 0.98 | ABCB11 (0.80) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL13960684 | 0.94 | ABCB11 (0.79) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL13960682 | 0.92 | ABCB11 (0.80) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL13960683 | 0.90 | ABCB11 (0.78) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL19200057 | 0.90 | ABCB11 (0.83) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL10112583 | 0.89 | ABCB11 (0.70) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL13278024 | 0.89 | ABCB11 (0.76) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL13468604 | 0.89 | ABCB11 (0.76) | ABCB11AKR1C3PTGFRPTGER3TBXA2R | |
| SCHEMBL15655151 | 0.89 | ABCB11 (0.76) | ABCB11AKR1C3PTGFRPTGER3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114370-B1 | NOVEL BIOMATERIALS FOR OCULAR DRUG DELIVERY AND A METHOD FOR MAKING AND USING SAME | ALLERGAN INC (US) | 2012-10-03 | — | — | EP | disclosed |
| EP-2425816-A2 | A pharmaceutical composition for use in treating an ocular disease or condition and a method for producing the composition | Allergan, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |
| EP-2114370-A2 | NOVEL BIOMATERIALS FOR OCULAR DRUG DELIVERY AND A METHOD FOR MAKING AND USING SAME | Allergan, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008094659-A2 | NOVEL BIOMATERIALS FOR OCULAR DRUG DELIVERY AND A METHOD FOR MAKING AND USING SAME | ALLERGAN, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008094675-A2 | NOVEL BIOMATERIALS AND METHODS FOR MAKING AND USING SAME | PHOTOBIOMED CORPORATION (US) | 2008-08-07 | — | — | WO | disclosed |