Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.83 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.83 |
| ▸ | PTGFR | P43088 | 7/20 | 0.66 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.66 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13468506 | 0.93 | ABCB11 (0.83) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| SCHEMBL20468095 | 0.93 | ABCB11 (0.83) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| SCHEMBL4875027 | 0.92 | ABCB11 (0.80) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| SCHEMBL15698208 | 0.92 | ABCB11 (0.80) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| SCHEMBL13960682 | 0.92 | ABCB11 (0.80) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| SCHEMBL13960684 | 0.91 | ABCB11 (0.79) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| Bimatoprost SCHEMBL14201686 | 0.91 | ABCB11 (1.00) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| Bimatoprost SCHEMBL15676045 | 0.91 | ABCB11 (1.00) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| Bimatoprost SCHEMBL10071736 | 0.91 | ABCB11 (1.00) | ABCB11AKR1C3PTGFRPTGER3MGLL | |
| Bimatoprost SCHEMBL22364345 | 0.91 | ABCB11 (1.00) | ABCB11AKR1C3PTGFRPTGER3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ABCB11 477/4885AKR1C3 622/4885PTGFR 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.