Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457581 | 0.91 | KCNH2 (0.45) | POLBGAAMGAMSIMGAM2 | |
| SCHEMBL9710527 | 0.82 | MAPT (0.42) | POLBGAATSHRMAPTMEN1 | |
| SCHEMBL9427047 | 0.81 | ALDH1A1 (0.50) | POLBGAAMGAMSIMGAM2 | |
| SCHEMBL9457589 | 0.81 | ALDH1A1 (0.42) | POLBGAAALDH1A1MAPTMEN1 | |
| SCHEMBL9457594 | 0.81 | POLB (0.39) | POLBALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL9710287 | 0.80 | POLB (0.46) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9457443 | 0.79 | AOC3 (0.52) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9710500 | 0.79 | BCL9 (0.39) | POLBGAATSHRMAPTMEN1 | |
| SCHEMBL9457601 | 0.79 | KCNH2 (0.47) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9458234 | 0.77 | MEN1 (0.43) | POLBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |