Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710287 | 0.96 | POLB (0.46) | KCNH2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9457581 | 0.88 | KCNH2 (0.45) | KCNH2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9457404 | 0.84 | MEN1 (0.44) | KCNH2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9457564 | 0.82 | KDM4E (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9457465 | 0.79 | POLB (0.42) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL9457482 | 0.78 | POLB (0.50) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL9710527 | 0.77 | MAPT (0.42) | KCNH2MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9710352 | 0.76 | POLB (0.46) | KCNH2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9457589 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9457594 | 0.75 | POLB (0.39) | MEN1KMT2APOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |