Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.41 |
| ▸ | CYP21A2 | P08686 | 8/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457891 | 0.91 | CYP3A4 (0.42) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL10498940 | 0.87 | CYP3A4 (0.41) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL10498950 | 0.87 | CYP3A4 (0.41) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL9489027 | 0.87 | CYP3A4 (0.44) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL9489020 | 0.87 | CYP3A4 (0.44) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL9489013 | 0.87 | CYP3A4 (0.44) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL9489858 | 0.85 | ALDH1A1 (0.48) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL10564539 | 0.84 | ADRA1A (0.49) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL10564528 | 0.84 | ADRA1A (0.49) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 | |
| SCHEMBL6967483 | 0.83 | CYP3A4 (0.49) | CYP3A4CYP19A1CYP21A2CYP17A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | claimed |
| EP-0065485-B1 | ARYLPHENYL ETHER DERIVATIVES AS MICROBICIDES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| EP-0065485-A2 | Arylphenyl ether derivatives as microbicides, process for their preparation and their application | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | claimed |
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0065485-A2 | Arylphenyl ether derivatives as microbicides, process for their preparation and their application | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | disclosed |