Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28824559 | 0.98 | GABRA1 (0.60) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL2771239 | 0.84 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL722841 | 0.83 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1CYP3A4SIGMAR1 | |
| SCHEMBL7195622 | 0.83 | ALDH1A1 (0.50) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL18245021 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL13324886 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL332763 | 0.82 | GABRA1 (0.79) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| Hydrochlorthiazide SCHEMBL27379144 | 0.82 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL22588537 | 0.81 | GABRA1 (0.65) | GABRA1GABRB2ALDH1A1POLBCYP3A4 | |
| SCHEMBL29449620 | 0.81 | GABRA1 (0.65) | GABRA1GABRB2ALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916755-A | Materials and methods for extending the shelf life of food products | JP实验室公司 | 2023-10-20 | — | — | CN | claimed |
| CN-115226722-B | Composition, preparation and application of isothiocyanate and avermectin B2 | 西北农林科技大学 | 2023-06-30 | — | — | CN | claimed |
| CN-112913849-A | Pesticide composition containing isothiocyanate compounds and application of pesticide composition in prevention and treatment of plant diseases | 兰州大学 | 2021-06-08 | — | — | CN | claimed |
| CN-106496459-A | A kind of bag for container film | 无锡三帝特种高分子材料有限公司 | 2017-03-15 | — | — | CN | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-105267967-A | Combined application of isothiocyanate-type compound and anti-cancer drug acting or affecting DNA | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2016-01-27 | — | — | CN | claimed |
| CN-104415332-A | Combined application between isothiocyanate-type compound and kinase inhibitor medicine in treatment of cancer | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2015-03-18 | — | — | CN | claimed |
| CN-104117064-A | Combined application of isothiocyanate compound and hormone medicine | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2014-10-29 | — | — | CN | claimed |
| WO-2010065329-A2 | NANOPARTICLES FOR CANCER TREATMENT | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-06-10 | — | — | WO | claimed |
| US-20060241178-A1 | Compositions and methods for treating lung cancer | IMMUNEGUARD LLC (US) | 2006-10-26 | — | — | US | claimed |
| WO-2004060365-A1 | COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER | AMERICAN HEALTH FOUNDATION (US) | 2004-07-22 | — | — | WO | claimed |
| CN-122012354-A | Lactobacillus plantarum strain LT400 and application thereof | 广西壮族自治区农业科学院 | 2026-05-12 | — | — | CN | disclosed |
| CN-115944617-B | Application of anti-endometrial cancer medicine of phenethyl isothiocyanate naturally occurring in cruciferous vegetables | 浙江大学医学院附属儿童医院 | 2025-02-11 | — | — | CN | disclosed |
| EP-3446689-B1 | ISOTHIOCYANATE COMPOUND FOR USE IN THE TREATMENT OF HYPERBILIRUBINEMIA | JC WUXI COMPANY INC (CN) | 2025-01-08 | — | — | EP | disclosed |
| CN-118873522-A | Application of isothiocyanate compound | 无锡杰西医药股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |
| US-5059692-A | NOVEL COMPOUNDS EXHIBITING A VASODILATING ACTIVITY AND INHIBITORY ACTIVITY FOR PLATELET AGGREGATION | HIDAKA HIROYOSHI (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0246366-A1 | Hydrogenation process for making rapid melting fats | THE PROCTER & GAMBLE COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4636574-A | Process for preparing arylisothiocyanates | ETHYL CORPORATION (US) | 1987-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | GABRA1 3626/4885GABRB2 3271/4885ALDH1A1 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.