SCHEMBL9458419

SCHEMBL9458419

CCC(=O)Br.c1cc2ccc1o2

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA9 Q16790 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
ALDH1A1 P00352 2/20 0.30
FFAR3 O14843 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL3926460 0.82 FFAR3 (0.53) SMN1; SMN2CES2CES1GAATDP1
Alcohol SCHEMBL8524158 0.75 ALDH1A1 (0.40) MEN1KMT2ATDP1ALDH1A1MAPT
SCHEMBL35764 0.74
Acetic Acid SCHEMBL11212519 0.73 FFAR3 (0.44) SMN1; SMN2CES2CES1MEN1KMT2A
Propanol SCHEMBL20590519 0.70 ALDH1A1 (0.33) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL10707564 0.70 AKR1C3 (0.38) KMT2AHTTTDP1ALDH1A1MAPT
Biphenyl SCHEMBL28874733 0.70 MAPT (0.59) SMN1; SMN2CES2CES1GAAMEN1
Ethyl Chloride SCHEMBL4465242 0.69 CTRC (0.32) TDP1
SCHEMBL11534019 0.68
Chloroacetic Acid SCHEMBL11683671 0.67 TSHR (0.53) SMN1; SMN2MEN1KMT2AHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5266585-A Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents CIBA-GEIGY CORPORATION (US) 1993-11-30 US disclosed