Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458476 | 0.81 | GBA1 (0.33) | GBA1 | |
| SCHEMBL7528266 | 0.76 | — | — | |
| SCHEMBL8990300 | 0.72 | HAO1 (0.33) | — | |
| SCHEMBL25175734 | 0.70 | CYP1A2 (0.34) | GBA1 | |
| SCHEMBL19449958 | 0.68 | CTDSP1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL3637280 | 0.67 | GBA1 (0.31) | GBA1 | |
| SCHEMBL17039191 | 0.67 | GBA1 (0.34) | GBA1 | |
| SCHEMBL3363728 | 0.67 | GPR119 (0.38) | KMT2ATSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL87245 | 0.66 | POLB (0.42) | KMT2ATSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL439945 | 0.66 | CTSS (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238602-A | Electrooptical cells | HOFFMANN LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-5013478-A | Electromagnetic radiation resistance; miscibility; dielectrics; rotation and guest/host cells | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4676604-A | RADIATION RESISTANCE; MISCIBILITY; ROTATION ELECTROPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-30 | — | — | US | disclosed |
| US-4565425-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1986-01-21 | — | — | US | disclosed |