Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458462 | 1.00 | HTR1A (0.62) | HTR1ADRD2 | |
| SCHEMBL9458466 | 1.00 | HTR1A (0.62) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458338 | 0.99 | HTR1A (0.61) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458335 | 0.99 | HTR1A (0.61) | HTR1ADRD2 | |
| SCHEMBL7845967 | 0.78 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL7835585 | 0.78 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL8100761 | 0.78 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL8099072 | 0.78 | HTR1A (0.43) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7851181 | 0.77 | HTR1A (0.42) | HTR1ADRD2 | |
| SCHEMBL8808944 | 0.77 | HTR1A (1.00) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422134-A1 | 5-HT SELECTIVE AGENTS. | ABBOTT LAB (US) | 1991-04-17 | — | — | EP | claimed |
| WO-1990006927-A1 | 5-HT SELECTIVE AGENTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | claimed |
| US-5244888-A | Hexahydroindenopyrroles and hexahydrobenzisoindoles | ABBOTT LABORATORIES (US) | 1993-09-14 | — | — | US | disclosed |
| US-5049564-A | Hypotensive, 5-hydroxytryptamine | ABBOTT LABORATORIES (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0422134-A1 | 5-HT SELECTIVE AGENTS. | ABBOTT LAB (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1990006927-A1 | 5-HT SELECTIVE AGENTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | disclosed |