Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458490 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HRH3KCNH2ALDH2 | |
| SCHEMBL10341638 | 0.92 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1HRH3KCNH2MAOA | |
| SCHEMBL10341639 | 0.92 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1HRH3KCNH2MAOA | |
| SCHEMBL10341649 | 0.91 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAOAMAOBLMNA | |
| SCHEMBL10341648 | 0.91 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAOAMAOBLMNA | |
| SCHEMBL9457920 | 0.90 | LMNA (0.38) | ALDH1A1L3MBTL1HRH3KCNH2MAOA | |
| SCHEMBL9457925 | 0.90 | LMNA (0.38) | ALDH1A1L3MBTL1HRH3KCNH2MAOA | |
| SCHEMBL10797375 | 0.88 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAOAMAOBLMNA | |
| SCHEMBL10797380 | 0.88 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAOAMAOBLMNA | |
| SCHEMBL9878746 | 0.84 | RARB (0.38) | ALDH1A1L3MBTL1MAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238602-A | Electrooptical cells | HOFFMANN LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0168683-B1 | LIQUID CRYSTALS WITH ALKENYL OR ALKENYLOXY GROUPS | F. HOFFMANN-LA ROCHE AG (CH) | 1990-11-28 | — | — | EP | disclosed |
| EP-0168683-A2 | Liquid crystals with alkenyl or alkenyloxy groups | F. HOFFMANN-LA ROCHE AG (CH) | 1986-01-22 | — | — | EP | disclosed |