Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753091 | 0.84 | POLB (0.47) | POLBP2RX7 | |
| SCHEMBL15428572 | 0.76 | POLB (0.43) | POLBNOTUMKDM4EMAPTCYP3A4 | |
| SCHEMBL10992734 | 0.76 | POLB (0.55) | POLBALDH1A1KDM4EGAAPKM | |
| Hydrochloric Acid SCHEMBL11473793 | 0.74 | POLB (0.53) | POLBALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL1491128 | 0.70 | POLB (0.53) | POLBNOTUMALDH1A1NPSR1GAA | |
| SCHEMBL7086206 | 0.70 | ALDH1A1 (0.42) | POLBALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL17861345 | 0.70 | POLB (0.41) | POLBALDH1A1NPSR1KDM4EGAA | |
| SCHEMBL17844085 | 0.70 | MAPK14 (0.43) | POLBALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10708284 | 0.70 | NOTUM (0.37) | NOTUMALDH1A1NPSR1HCAR1 | |
| SCHEMBL17844034 | 0.69 | POLB (0.52) | POLBALDH1A1KDM4EGAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256634-A | Herbicidal agents based on pyrazole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5104439-A | HERBICIDAL AGENTS BASED ON PYRAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0154115-B1 | HERBICIDAL COMPOSITIONS BASED ON DERIVATIVES OF PYRAZOLES | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |
| US-4614533-A | Herbicidal 5-amino-1-phenylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0154115-A1 | Herbicidal compositions based on derivatives of pyrazoles | BAYER AG (DE) | 1985-09-11 | — | — | EP | disclosed |