Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.71 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.71 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945167 | 0.92 | S1PR1 (0.81) | S1PR1S1PR5S1PR4 | |
| SCHEMBL945165 | 0.92 | S1PR1 (0.81) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2565081 | 0.90 | S1PR1 (0.85) | S1PR1S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL950192 | 0.88 | S1PR1 (0.63) | S1PR1S1PR5S1PR4KMT2A | |
| SCHEMBL948216 | 0.86 | S1PR1 (0.69) | S1PR1S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL945022 | 0.84 | S1PR1 (0.64) | S1PR1S1PR5S1PR4KMT2A | |
| SCHEMBL2567881 | 0.83 | S1PR1 (1.00) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2562414 | 0.83 | S1PR1 (1.00) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2565705 | 0.83 | S1PR1 (1.00) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2566711 | 0.83 | S1PR1 (0.83) | S1PR1S1PR5S1PR4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005295-A1 | MODULATORS OF THE SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |