Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458706 | 0.79 | KMT2A (0.44) | NPBWR1MCHR1MAPK1MAPTRECQL | |
| SCHEMBL1884450 | 0.74 | FGFR1 (0.45) | SCN9ANPC1RAB9ALMNAGAA | |
| SCHEMBL3148079 | 0.73 | TDP1 (0.50) | MAPK1CHRM5SCN9ANPC1RAB9A | |
| SCHEMBL6201722 | 0.70 | FFAR4 (0.41) | MAPK1CHRM5SCN9ANPC1RAB9A | |
| SCHEMBL21339745 | 0.70 | NPC1 (0.47) | MAPK1SCN9ANPC1RAB9AGMNN | |
| SCHEMBL10737936 | 0.69 | CHRM5 (0.35) | NPBWR1MCHR1MAPK1MAPTRECQL | |
| SCHEMBL10738468 | 0.69 | TRPA1 (0.34) | NPBWR1MCHR1MAPK1MAPTRECQL | |
| SCHEMBL14843789 | 0.69 | HCRTR1 (0.40) | CHRM5SCN5AHCRTR1 | |
| SCHEMBL28304122 | 0.69 | SMURF1 (0.41) | NPBWR1MCHR1MAPK1MAPTRECQL | |
| SCHEMBL15332944 | 0.68 | TDP1 (0.49) | L3MBTL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256634-A | Herbicidal agents based on pyrazole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5104439-A | HERBICIDAL AGENTS BASED ON PYRAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0154115-B1 | HERBICIDAL COMPOSITIONS BASED ON DERIVATIVES OF PYRAZOLES | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |
| US-4614533-A | Herbicidal 5-amino-1-phenylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0154115-A1 | Herbicidal compositions based on derivatives of pyrazoles | BAYER AG (DE) | 1985-09-11 | — | — | EP | disclosed |