Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535814 | 0.78 | KMT2A (0.38) | MDM2 | |
| SCHEMBL17070911 | 0.66 | ALDH1A1 (0.40) | — | |
| SCHEMBL10261542 | 0.55 | ESR1 (0.39) | — | |
| SCHEMBL623278 | 0.55 | PTPN1 (0.39) | — | |
| SCHEMBL3073195 | 0.54 | ALDH1A1 (0.36) | — | |
| SCHEMBL3073191 | 0.54 | ALDH1A1 (0.36) | — | |
| SCHEMBL2804521 | 0.54 | ALDH1A1 (0.37) | — | |
| SCHEMBL1713659 | 0.53 | MAPT (0.43) | — | |
| SCHEMBL3078902 | 0.51 | ALDH1A1 (0.36) | — | |
| SCHEMBL3080913 | 0.51 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260451-A | Enzyme inhibitors | MERCKLE GMBH (DE) | 1993-11-09 | — | — | US | disclosed |