SCHEMBL9458908

SCHEMBL9458908

CCCCN(C)c1ccc(C(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
ALOX5 P09917 2/20 0.51
RARB P10826 6/20 0.49
PLA2G2A P14555 1/20 0.48
TRPV1 Q8NER1 1/20 0.48
HCAR3 P49019 1/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA9 Q16790 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
ABCC2 Q92887 1/20 0.46
SLC22A12 Q96S37 1/20 0.46
UGT1A7 Q9HAW7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29114273 0.95 PTGES (0.51) MAPTALOX5RARBPLA2G2ATRPV1
SCHEMBL9063289 0.93 PTGES (0.53) MAPTALOX5RARBPLA2G2ATRPV1
SCHEMBL8650216 0.93 PTGES (0.53) MAPTALOX5RARBPLA2G2ATRPV1
SCHEMBL11044465 0.93 PTGES (0.53) MAPTALOX5RARBPLA2G2ATRPV1
SCHEMBL11146761 0.89 HCAR3 (0.58) ALOX5RARBPLA2G2ATRPV1HCAR3
SCHEMBL14207379 0.86 MEN1 (0.46) PLA2G2AHCAR3TP53TSHRMEN1
SCHEMBL27846955 0.85 MEN1 (0.59) MAPTALOX5RARBPLA2G2ATRPV1
SCHEMBL27525034 0.84 MAPT (0.53) MAPTTRPV1
Hydrochloric Acid SCHEMBL1335201 0.84 MEN1 (0.45) PLA2G2AHCAR3TP53TSHRMEN1
SCHEMBL472266 0.84 EGFR (0.58) MAPTALOX5RARBTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5230874-A Ultraviolet radiation absorbers THE PROCTER & GAMBLE COMPANY (US) 1993-07-27 US disclosed
US-5229107-A Sunscreen agents, sunscreen compositions and methods for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1993-07-20 US disclosed
US-5229106-A Sunscreen agents, sunscreen compositions and method for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1993-07-20 US disclosed
US-5160731-A Unsaturated ketones containing ester or amide groups, UVA and UVB absorbers THE PROCTER & GAMBLE COMPANY (US) 1992-11-03 US disclosed
EP-0255157-B1 NOVEL SUNSCREEN AGENTS, SUNSCREEN COMPOSITIONS AND METHODS FOR PREVENTING SUNBURN THE PROCTER & GAMBLE COMPANY (US) 1992-08-12 EP disclosed
US-5087445-A Sunscreen agents absorbing both the UVA and UVB wavelengths comprising a chromophoricester of benzophenone; daily use as a cosmetic RICHARDSON-VICKS, INC. (US) 1992-02-11 US disclosed
US-5041282-A Topical application of sunscreen agent THE PROCTER & GAMBLE COMPANY (US) 1991-08-20 US disclosed
US-4999186-A P-aminobenzoic acid derivatives; chromogens THE PROCTER & GAMBLE COMPANY (US) 1991-03-12 US disclosed
EP-0255157-A2 Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1988-02-03 EP disclosed
US-4021471-A Formamidines useful as ultraviolet light absorbers GIVAUDAN CORPORATION (US) 1977-05-03 US disclosed