Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.64 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | TET3 | O43151 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6056810 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL5703613 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL8984407 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL6056821 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL6056894 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL8984535 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL327411 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL8984493 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL7172857 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL3793029 | 1.00 | GPR84 (0.64) | GPR84FFAR1TET2KDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116399-A1 | Tumor Homing Statin Derivatives | Da Zen Theranostics, Inc. (US) | 2023-04-13 | — | — | US | claimed |
| CN-114686092-A | Photocureable coating capable of being used for metal protection and preparation method thereof | 中海油常州涂料化工研究院有限公司 | 2022-07-01 | — | — | CN | claimed |
| US-20210008217-A1 | Tumor Homing Statin Derivatives | Da Zen Theranostics, Inc. (US) | 2021-01-14 | — | — | US | claimed |
| EP-3763389-A1 | TUMOR HOMING STATIN DERIVATIVES | Da Zen Theranostics Inc. (US) | 2021-01-13 | — | — | EP | claimed |
| CN-111068064-A | Composition comprising fatty acid or derivative thereof and dihydroxyheptanoic acid derivative | 黄泳华 | 2020-04-28 | — | — | CN | claimed |
| CN-110590638-A | Tumor-targeted statin derivative, pharmaceutical formulation and application | 德珍(中国)医疗科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| US-9296702-B2 | Rosuvastatin enantiomer compounds | SCALLEN, MICHAEL | 2016-03-29 | — | — | US | claimed |
| US-8729092-B2 | Rosuvastatin enantiomer compounds | SCALLEN, MICHAEL | 2014-05-20 | — | — | US | claimed |
| US-20140080788-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2014-03-20 | — | — | US | claimed |
| EP-2049102-A2 | POLYMORPHIC FORMS OF AN HMG-COA REDUCTASE INHIBITOR AND USES THEREOF | RANBAXY LABORATORIES, LTD. (IN) | 2009-04-22 | — | — | EP | claimed |
| WO-2004106299-A2 | SUBSTITUTED PYRROLE DERIVATIVES AND THEIR USE AS HMG-CO INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-09 | — | — | WO | claimed |
| EP-1470106-A1 | METHOD OF MANUFACTURING AN AMORPHOUS FORM OF THE HEMI-CALCIUM SALT OF (3R, 5R) 7- 3-PHENYL-4-PHENYLCARBAMOYL-2-(4-FLUOROPHENYL)-5-ISOPROPYL-PYRROL-1-YL!-3, 5-DIHYDROXYHEPTANOIC ACID (ATORVASTATIN) | Zentiva, A.S. (CZ) | 2004-10-27 | — | — | EP | claimed |
| WO-2004027075-A2 | CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STAIN INTERMEDIATES | DIVERSA CORPORATION (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2003068739-A1 | METHOD OF MANUFACTURING AN AMORPHOUS FORM OF THE HEMI-CALCIUM SALT OF (3R, 5R) 7- 3-PHENYL-4-PHENYLCARBAMOYL-2-(4-FLUOROPHENYL)-5-ISOPROPYL-PYRROL-1-YL!-3, 5-DIHYDROXYHEPTANOIC ACID (ATORVASTATIN) | ZENTIVA A.S. (CZ) | 2003-08-21 | — | — | WO | claimed |
| JP-2003518086-A | — | — | 2003-06-03 | — | — | JP | claimed |
| EP-1242365-A1 | ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALISED AUXILIARY ARM | OM Pharma (CH) | 2002-09-25 | — | — | EP | claimed |
| WO-2001046126-A1 | ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALISED AUXILIARY ARM | OM PHARMA (CH) | 2001-06-28 | — | — | WO | claimed |
| EP-0494120-A1 | HMG-CoA reductase inhibitors | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-07-08 | — | — | EP | claimed |
| EP-0480986-A1 | 6-(HYDRONAPHTYL-1-ETHYL)-4-HYDROXY-3,4,5,6-TETRAHYDRO-2H-PYRAN-2-ONES AND THE CORRESPONDING HYDROXY ACIDS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-04-22 | — | — | EP | claimed |
| US-4775681-A | Method of treating fungal infections with trans-6-[2-substitutedpyrrol-1-yl)alkyl]-4-hydroxypyran-2-ones | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116399-A1 | Tumor Homing Statin Derivatives | HMGCR, DHCR7, DHODH | GPR84 1496/4885FFAR1 953/4885TET2 3017/4885 |
| US-20140080788-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | GRK5, GPBAR1, GPR55 | GPR84 60/4885FFAR1 31/4885TET2 4168/4885 |
| US-20210008217-A1 | Tumor Homing Statin Derivatives | HMGCR, DHCR7, DHODH | GPR84 1496/4885FFAR1 953/4885TET2 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.