Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844034 | 0.82 | POLB (0.52) | KDRPOLBKDM4EALDH1A1TSHR | |
| SCHEMBL8767333 | 0.81 | POLB (0.40) | KDRPOLBSRCRIPK2EGFR | |
| SCHEMBL9458856 | 0.81 | GABRB3 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10609139 | 0.80 | KDR (0.42) | KDRSRCRIPK2EGFRBRAF | |
| SCHEMBL406517 | 0.78 | POLB (0.57) | KDRPOLBMEN1KMT2ANPSR1 | |
| SCHEMBL7082414 | 0.77 | MAPT (0.41) | KDRPOLBSMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL10684842 | 0.75 | POLB (0.41) | KDRPOLBKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL15428572 | 0.74 | POLB (0.43) | POLBMEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL9822871 | 0.74 | POLB (0.37) | KDRPOLBKDM4EMAPTGABRP | |
| SCHEMBL10496963 | 0.74 | POLB (0.37) | KDRPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256634-A | Herbicidal agents based on pyrazole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5104439-A | HERBICIDAL AGENTS BASED ON PYRAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0201852-B1 | AGENT AGAINST NOXIOUS PLANTS BASED ON PYRAZOL DERIVATIVES | BAYER AG (DE) | 1990-08-16 | — | — | EP | disclosed |
| US-4945165-A | Insecticide, miticide, nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-31 | — | — | US | disclosed |
| US-4820725-A | MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-11 | — | — | US | disclosed |
| EP-0222253-B1 | SUBSTITUTED 5-AMINO-1-ARYL-PYRAZOLES | BAYER AG (DE) | 1989-04-05 | — | — | EP | disclosed |
| US-4804675-A | 1-aryl-4-alkylthiopyrazol-5-amine derivatives, composition containing them, and method of using them to combat insects, arachnids, and nematodes | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| EP-0290904-A1 | 1-Aryl-3-halogenoalkyl-4-halogene pyrazols | BAYER AG (DE) | 1988-11-17 | — | — | EP | disclosed |
| EP-0154115-B1 | HERBICIDAL COMPOSITIONS BASED ON DERIVATIVES OF PYRAZOLES | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |
| US-4695308-A | Herbicidal substituted 5-amino-1-aryl-pyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0222253-A1 | Substituted 5-amino-1-aryl-pyrazoles | BAYER AG (DE) | 1987-05-20 | — | — | EP | disclosed |
| EP-0216102-A1 | 1-Arylpyrazoles | BAYER AG (DE) | 1987-04-01 | — | — | EP | disclosed |
| EP-0201852-A2 | Agent against noxious plants based on pyrazol derivatives | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |
| US-4614533-A | Herbicidal 5-amino-1-phenylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0154115-A1 | Herbicidal compositions based on derivatives of pyrazoles | BAYER AG (DE) | 1985-09-11 | — | — | EP | disclosed |