Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459015 | 0.81 | KDR (0.51) | POLBKDRKDM4ERIPK2EGFR | |
| SCHEMBL10496963 | 0.80 | POLB (0.37) | POLBKDRKDM4E | |
| SCHEMBL9458856 | 0.77 | GABRB3 (0.54) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL17844034 | 0.75 | POLB (0.52) | POLBKDRKDM4E | |
| SCHEMBL7082414 | 0.74 | MAPT (0.41) | POLBKDRKDM4EGABRA2GABRB2 | |
| SCHEMBL9822871 | 0.71 | POLB (0.37) | POLBKDRKDM4EGABRA2GABRB2 | |
| SCHEMBL8767317 | 0.69 | L3MBTL1 (0.49) | KDM4ETRPV4 | |
| SCHEMBL10389922 | 0.69 | POLB (0.35) | POLBKDRGABRA2GABRB2GABRP | |
| SCHEMBL7086689 | 0.69 | GABRB3 (0.45) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL1727194 | 0.68 | POLB (0.47) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788484-A1 | 2-CHLORO-N- 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AG (DE) | 1997-08-13 | — | — | EP | claimed |
| WO-1996012707-A1 | 2-CHLORO-N-[1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-02 | — | — | WO | claimed |
| JP-1066170-A | — | — | None | — | — | JP | disclosed |
| EP-0788484-A1 | 2-CHLORO-N- 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996012707-A1 | 2-CHLORO-N-[1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-02 | — | — | WO | disclosed |
| EP-0303906-A1 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-22 | — | — | EP | disclosed |
| EP-0303153-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-15 | — | — | EP | disclosed |