Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333892 | 0.83 | NPC1 (0.49) | ESR1KCNH2NPC1RAB9AFOLH1 | |
| SCHEMBL4462033 | 0.80 | NPC1 (0.67) | ESR1KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL6679690 | 0.80 | NPC1 (0.67) | ESR1KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL8420771 | 0.80 | NPC1 (0.67) | ESR1KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL9099482 | 0.79 | ESR1 (0.55) | ESR1KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL2953753 | 0.78 | ATM (0.47) | FOLH1 | |
| SCHEMBL6679784 | 0.77 | ESR1 (0.56) | ESR1KCNH2NPC1RAB9ALMNA | |
| SCHEMBL9459738 | 0.77 | ESR1 (0.56) | ESR1KCNH2NPC1RAB9AELANE | |
| SCHEMBL9459728 | 0.77 | ESR1 (0.56) | ESR1KCNH2NPC1RAB9AELANE | |
| SCHEMBL6679779 | 0.77 | ESR1 (0.56) | ESR1KCNH2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262333-A | Fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-11-16 | — | — | US | disclosed |