Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459072 | 0.83 | ESR1 (0.60) | NPC1RAB9AFOLH1HTTMEN1 | |
| SCHEMBL2953753 | 0.81 | ATM (0.47) | FOLH1 | |
| SCHEMBL6889929 | 0.81 | MEN1 (0.58) | NPC1RAB9AFOLH1HTTMEN1 | |
| SCHEMBL157592 | 0.80 | FOLH1 (0.53) | FOLH1HTTMEN1KMT2ACLCN2 | |
| SCHEMBL18422575 | 0.80 | LMNA (0.50) | NPC1RAB9ALMNAESR1KCNH2 | |
| SCHEMBL4328756 | 0.80 | CA12 (0.43) | NPC1RAB9AHTTMEN1KMT2A | |
| SCHEMBL17799517 | 0.79 | FOLH1 (0.52) | FOLH1HTTMEN1KMT2ACLCN2 | |
| SCHEMBL11141533 | 0.77 | FOLH1 (0.50) | FOLH1CLCN2TSHRALDH1A1ALOX15 | |
| SCHEMBL264745 | 0.77 | FOLH1 (0.50) | FOLH1CLCN2TSHRALDH1A1ALOX15 | |
| SCHEMBL6839201 | 0.77 | FOLH1 (0.50) | FOLH1CLCN2TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |