Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459738 | 1.00 | ESR1 (0.56) | ESR1KCNH2MEN1KMT2APOLB | |
| SCHEMBL9459728 | 1.00 | ESR1 (0.56) | ESR1KCNH2MEN1KMT2APOLB | |
| SCHEMBL9180429 | 0.87 | MEN1 (0.47) | ESR1KCNH2MEN1KMT2APOLB | |
| SCHEMBL3341416 | 0.79 | MEN1 (0.55) | MEN1KMT2APOLBCYP2C19NPC1 | |
| SCHEMBL9459072 | 0.77 | ESR1 (0.60) | ESR1KCNH2MEN1KMT2APOLB | |
| SCHEMBL6294901 | 0.77 | ALDH1A1 (0.51) | KCNH2MEN1KMT2APOLBCYP2C19 | |
| Hydrochloric Acid SCHEMBL9219131 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2APOLBCYP2C19NPC1 | |
| SCHEMBL7306213 | 0.76 | POLB (0.49) | MEN1KMT2APOLBCYP2C19NPC1 | |
| SCHEMBL11691410 | 0.76 | KMT2A (0.61) | ESR1KCNH2MEN1KMT2AMMP1 | |
| SCHEMBL11691407 | 0.76 | KMT2A (0.61) | ESR1KCNH2MEN1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262333-A | Fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-11-16 | — | — | US | disclosed |