Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460527 | 1.00 | HPGD (0.55) | HPGDALDH1A1APOBEC3AAPOBEC3GLMNA | |
| SCHEMBL9132246 | 0.92 | HPGD (0.47) | HPGDALDH1A1APOBEC3AAPOBEC3GLMNA | |
| SCHEMBL9136912 | 0.92 | HPGD (0.47) | HPGDALDH1A1APOBEC3AAPOBEC3GLMNA | |
| SCHEMBL9136915 | 0.89 | APOBEC3A (0.48) | HPGDALDH1A1APOBEC3AAPOBEC3GTSHR | |
| SCHEMBL9132253 | 0.89 | APOBEC3A (0.48) | HPGDALDH1A1APOBEC3AAPOBEC3GTSHR | |
| Terephthalic Acid SCHEMBL11375372 | 0.89 | APOBEC3A (0.61) | HPGDALDH1A1APOBEC3AAPOBEC3GTSHR | |
| Terephthalic Acid SCHEMBL11371951 | 0.89 | APOBEC3A (0.61) | HPGDALDH1A1APOBEC3AAPOBEC3GTSHR | |
| Tetramethylammonium Ion SCHEMBL9459712 | 0.85 | HPGD (0.58) | HPGDALDH1A1LMNAL3MBTL1RXRA | |
| SCHEMBL689927 | 0.82 | HPGD (0.69) | HPGDALDH1A1LMNAL3MBTL1RXRA | |
| SCHEMBL701728 | 0.80 | TSHR (0.60) | HPGDALDH1A1APOBEC3AAPOBEC3GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274184-A | Aryl sulphide, aryl sulphoxide and aryl sulphone compounds | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |