Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 6/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 4/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.58 |
| ▸ | HTR3B | O95264 | 2/20 | 0.58 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.58 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.58 |
| ▸ | HTR5A | P47898 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460473 | 1.00 | HTR4 (0.61) | HTR4ACHEDRD2DRD4DRD3 | |
| SCHEMBL9460481 | 1.00 | HTR4 (0.61) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9460956 | 0.99 | HTR4 (0.60) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9460954 | 0.99 | HTR4 (0.60) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9460955 | 0.99 | HTR4 (0.60) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9460967 | 0.98 | MAPK1 (0.59) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9460964 | 0.98 | MAPK1 (0.59) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9460962 | 0.98 | MAPK1 (0.59) | HTR4ACHEDRD2DRD4DRD3 | |
| Lirexapride SCHEMBL384567 | 0.89 | HTR4 (0.50) | HTR4ACHEDRD2DRD4DRD3 | |
| SCHEMBL8051781 | 0.81 | HTR4 (0.64) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5097805-A | — | — | None | — | — | JP | disclosed |
| US-5273983-A | 2-Piperidinylmethylcyclohexylaminocarbonyl-substituted benzene | LABORATORIES JACQUES LOGEAIS (FR) | 1993-12-28 | — | — | US | disclosed |
| JP-H0597805-A | NEW CYCLOHEXYLBENZAMIDE DERIVATIVE, ITS PREPARATION AND ITS USE FOR PHARMACEUTIC | LAB JACQUES LOGEAIS | 1993-04-20 | — | — | JP | disclosed |