SCHEMBL19463514

SCHEMBL19463514

Cc1nc(C)nc(C(=O)OCc2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.56
KMT2A Q03164 3/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A3 Q01959 1/20 0.56
ALDH1A1 P00352 7/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 1/20 0.53
LMNA P02545 2/20 0.51
RAB9A P51151 5/20 0.51
TSHR P16473 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
L3MBTL1 Q9Y468 4/20 0.48
MAPK1 P28482 3/20 0.48
CYP3A4 P08684 1/20 0.48
STAT1 P42224 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
POLB P06746 1/20 0.47
ATM Q13315 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19928471 0.97 TDP1 (0.56) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL21131754 0.90 TDP1 (0.49) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL18630437 0.90 TDP1 (0.49) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL14768871 0.88 TDP1 (0.66) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL19901463 0.87 RAB9A (0.47) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL20348533 0.87 TDP1 (0.56) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL20272108 0.86 ALDH1A1 (0.46) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL20305865 0.84 TDP1 (0.50) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL20782415 0.84 TDP1 (0.53) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL22005504 0.83 TDP1 (0.56) TDP1KMT2ASLC6A2SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132589-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
EP-3799144-B1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2022-06-01 EP disclosed
US-11251376-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-15 US disclosed
US-10897011-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-19 US disclosed
US-10875825-B2 Amine-based compound and organic light-emitting device including the same Samsung Display Co., Lid. (KR) 2020-12-29 US disclosed
US-20200303647-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-09-24 US disclosed
EP-3712971-A1 THERMOELECTRIC CONVERSION DEVICE ASAHI FR R&D Co., Ltd. (JP) 2020-09-23 EP disclosed
US-20190131535-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-02 US disclosed
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20190055187-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-21 US disclosed
US-10040794-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-08-07 US disclosed
US-9842995-B2 Amine-based compounds and organic light-emitting devices comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-12-12 US disclosed
US-9825231-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US disclosed
US-9818952-B2 Condensed cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9793496-B2 Condensed-cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-17 US disclosed
US-9793494-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055187-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME VDAC1, IARS2, TRMT1L TDP1 1344/4885KMT2A 845/4885SLC6A2 375/4885
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same OCIAD1, OXA1L, OCIAD2 TDP1 851/4885KMT2A 3120/4885SLC6A2 4655/4885
US-11251376-B2 Heterocyclic compound and organic light-emitting device including the same LAGE3, DDT, AOC2 TDP1 2051/4885KMT2A 1290/4885SLC6A2 2300/4885
US-20190131535-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LAGE3, DDT, AOC2 TDP1 2051/4885KMT2A 1290/4885SLC6A2 2300/4885
US-20230132589-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME PPOX, PER2, CRY1 TDP1 1545/4885KMT2A 3751/4885SLC6A2 1892/4885
US-10040794-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNE2, CRY2 TDP1 3107/4885KMT2A 1935/4885SLC6A2 4704/4885
US-10875825-B2 Amine-based compound and organic light-emitting device including the same VDAC1, IARS2, TRMT1L TDP1 1344/4885KMT2A 845/4885SLC6A2 375/4885
US-20200303647-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SLC1A2, SLC18A2, TMEM109 TDP1 1487/4885KMT2A 961/4885SLC6A2 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.