Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735542 | 0.92 | NPC1 (0.35) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL9179117 | 0.89 | NPC1 (0.42) | NPC1RAB9ATYRGAATSHR | |
| SCHEMBL10788413 | 0.79 | NPC1 (0.53) | NPC1RAB9ATYRGAATSHR | |
| SCHEMBL7081279 | 0.77 | SMN1; SMN2 (0.38) | NPC1RAB9ATYRALDH1A1HSD17B10 | |
| SCHEMBL9183011 | 0.72 | NPC1 (0.58) | NPC1RAB9ATYRGAATSHR | |
| SCHEMBL9460562 | 0.71 | CNR1 (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3279274 | 0.70 | ALDH1A1 (0.55) | NPC1RAB9AHTTNPSR1KDM4E | |
| SCHEMBL7521249 | 0.70 | KDM4E (0.31) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3278042 | 0.70 | NPC1 (0.45) | NPC1RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL11616637 | 0.70 | NPC1 (0.43) | NPC1RAB9AGABRA1GABRB1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262541-A | Reaction with sugar as a reducing agent | FAIRMONT CHEMICAL COMPANY, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-4780541-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-10-25 | — | — | US | disclosed |