Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615531 | 0.93 | NPC1 (0.50) | NPC1RAB9ATYRMEN1KMT2A | |
| SCHEMBL10788413 | 0.91 | NPC1 (0.53) | NPC1RAB9ATYRLMNAPOLB | |
| SCHEMBL466590 | 0.81 | NPC1 (0.47) | NPC1RAB9ATYRLMNAPOLB | |
| SCHEMBL2590802 | 0.80 | NPC1 (0.42) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL11622645 | 0.80 | NPC1 (0.47) | NPC1RAB9ATYRMEN1KMT2A | |
| SCHEMBL9183011 | 0.79 | NPC1 (0.58) | NPC1RAB9ATYRLMNAPOLB | |
| SCHEMBL9269913 | 0.79 | NPC1 (0.42) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL11620211 | 0.76 | NPC1 (0.45) | NPC1RAB9ATYRLMNAPOLB | |
| SCHEMBL11618064 | 0.75 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL31155592 | 0.75 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127586-A | HYDROXYPHENYL BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1978-11-28 | — | — | US | disclosed |