Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461045 | 0.86 | ALDH1A1 (0.48) | HTTSMN1; SMN2KDM4ELMNAUSP2 | |
| SCHEMBL9461234 | 0.81 | ALDH1A1 (0.47) | HTTSMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL1923718 | 0.81 | KDM4E (0.49) | HTTSMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL1922940 | 0.76 | KDM4E (0.45) | SMN1; SMN2KDM4ELMNAPOLBALDH1A1 | |
| SCHEMBL8686002 | 0.75 | CYP1A2 (0.50) | SMN1; SMN2KDM4ELMNAUSP2ALDH1A1 | |
| SCHEMBL10576118 | 0.74 | SMN1; SMN2 (0.45) | HTTSMN1; SMN2LMNAUSP2POLB | |
| SCHEMBL1921603 | 0.74 | THRB (0.45) | HTTSMN1; SMN2MAPK1TSHRALDH1A1 | |
| SCHEMBL1719546 | 0.74 | MAPK8 (0.41) | HTTKDM4EMAPK1TSHRALDH1A1 | |
| SCHEMBL11074441 | 0.72 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2LMNAUSP2POLB | |
| SCHEMBL12479132 | 0.72 | KDM4E (0.43) | HTTSMN1; SMN2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5186736-A | Pre- and postemergence | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5053072-A | HETEROCYCLIC N-ACYLSULFONAMIDES, AND THEIR USE AS HERBICIDES OR GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |