Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462405 | 1.00 | PKM (0.51) | PKMCHRM3KDM4ELMNAKCNH2 | |
| SCHEMBL9462088 | 1.00 | PKM (0.51) | PKMCHRM3KDM4ELMNAKCNH2 | |
| SCHEMBL9462420 | 1.00 | PKM (0.51) | PKMCHRM3KDM4ELMNAKCNH2 | |
| SCHEMBL9292726 | 1.00 | PKM (0.51) | PKMCHRM3KDM4ELMNAKCNH2 | |
| SCHEMBL2110500 | 0.81 | GAA (0.65) | CHRM3KDM4ELMNAKCNH2ALDH1A1 | |
| SCHEMBL18539303 | 0.81 | GAA (0.65) | CHRM3KDM4ELMNAKCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4154192 | 0.80 | GAA (0.63) | CHRM3KDM4ELMNAKCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4668030 | 0.80 | GAA (0.63) | CHRM3KDM4ELMNAKCNH2ALDH1A1 | |
| SCHEMBL9292241 | 0.77 | CHRM3 (0.67) | PKMCHRM3KCNH2DRD3 | |
| SCHEMBL15800706 | 0.76 | CCR3 (0.70) | KDM4ELMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182284-A | Antiasthmatic agent, antiallergen, antiinflammatory agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0465659-A1 | PIPERAZINE COMPOUND, PRODUCTION THEREOF, AND MEDICINAL USE THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | disclosed |